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The present invention relates to rosuvastatin enantiomer compounds having 3r,5r , 3s,5r , or 3s,5s configurations, which maximize or normalize cellular phenotypic expression and that are broadly useful in the treatment of a wide variety of human diseases, including cancer, atherosclerosis, and immune system diseases or disorders.

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The seventh day after admission, treatment with one of three statins atorvastatin 20 mg day, pitavastatin 4 mg day, or rosuvastatin 5 mg day.

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Results the incremental cost per quality-adjusted life-year qaly gained with rosuvastatin 20 mg over simvastatin or atorvastatin 40 mg ranged from sek88,113 rosuvastatin 20 mg versus simvastatin 40 mg; framingham risk 30 ; net avoidance of 34 events 1000 patients to sek497,542 versus atorvastatin 40 mg framingham risk 20 ; net avoidance of 11 events 1000 patients over a lifetime horizon.

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Because of the importance of endothelialization in aneurysm treatment, we explored the effect of rosuvastatin on epc mobilization and activity in the treatment of intracranial aneurysms.

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